NY
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88 RESULTS WITHIN 50km FROM Pittsburgh, United States
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
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Ginsenoside Rd is a natural triterpenoid compound found in the roots of Panax ginseng C. A. Mey. Ginsenoside Re shows antioxidant activities. By preventing oxygen free radicals from attacking the cell membranes Ginsenoside-Rd exhibites oxygen-glucose dep... read more
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Ginsenoside Rd is a natural triterpenoid compound found in the roots of Panax ginseng C. A. Mey. Ginsenoside Re shows antioxidant activities. By preventing oxygen free radicals from attacking the cell membranes Ginsenoside-Rd exhibites oxygen-glucose dep... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
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WITHAFERIN A also referred to as D004 NSC 101088 used as an important medicinal herb for over 3000 years is a steroidal lactone derived from Acnistus arborescens Withania somnifera and other members of Solanaceae family. This natural product has wide range of pharmacological application comprising of anti-obesity anti-inflammatory anti-neoplastic antiangiogenic etc. WITHAFERIN A inhibits endothelial cells (HUVEC) sprouting (in vitro: IC50 = 12 nM and in vivo) activation of IKKβ (IC50= 0.5-1 μM) chymotrypsin-like activity of the 20S proteasome and cell proliferation of uveal melanoma cells (IC50= 0.90 1.66 and 2.42 μM for OMM2.3 92.1 and MEL290 cells respectively). In... read more
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WITHAFERIN A also referred to as D004 NSC 101088 used as an important medicinal herb for over 3000 years is a steroidal lactone derived from Acnistus arborescens Withania somnifera and other members of Solanaceae family. This natural product has wide range of pharmacological application comprising of anti-obesity anti-inflammatory anti-neoplastic antiangiogenic etc. WITHAFERIN A inhibits endothelial cells (HUVEC) sprouting (in vitro: IC50 = 12 nM and in vivo) activation of IKKβ (IC50= 0.5-1 μM) chymotrypsin-like activity of the 20S proteasome and cell proliferation of uveal melanoma cells (IC50= 0.90 1.66 and 2.42 μM for OMM2.3 92.1 and MEL290 cells respectively). In... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
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Kaempferol is a natural flavonol a type of flavonoid that has been isolated from plant sources.... read more
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Kaempferol is a natural flavonol a type of flavonoid that has been isolated from plant sources.... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
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Hyaluronic Acid Sodium Salt is sodium salt form of Hyaluronic Acid. Hyaluronic acid a mucopolysaccharide with high-viscosity traditionally extracted from rooster combs but now it is mainly produced via streptococcal fermentation.... read more
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Hyaluronic Acid Sodium Salt is sodium salt form of Hyaluronic Acid. Hyaluronic acid a mucopolysaccharide with high-viscosity traditionally extracted from rooster combs but now it is mainly produced via streptococcal fermentation.... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
At BOC Sciences our expertise in multi-disciplinary sciences offers integration drug discovery services to our clients in pharmaceutical industries small business and research institutes across the world. We are here to help you discovering and characterizing novel drug candidates for preclinical development from hit ID to IND. Our experienced expertise in total synthesis and methodology development delivers data-driven research in innovative and reliable science you can trust to progress your drug discovery programs.... read more
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At BOC Sciences our expertise in multi-disciplinary sciences offers integration drug discovery services to our clients in pharmaceutical industries small business and research institutes across the world. We are here to help you discovering and characterizing novel drug candidates for preclinical development from hit ID to IND. Our experienced expertise in total synthesis and methodology development delivers data-driven research in innovative and reliable science you can trust to progress your drug discovery programs.... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Superparamagnetic iron oxide microbeads have broad applications in biomedicine such as magnetic cell isolation and biomolecules purification magnetic resonance imaging of diseased tissues magnetic immunoassay targeted delivery of drugs and antigens hyperthermia aided chemo/radiotherapy and so on. BOC Sciences offers high-quality superparamagnetic iron oxide microbeads. Our products include various-sized magnetic beads with different coupling groups for the conjugation of biomolecules. We have established a high-level platform that involves many scientists and a full set of instruments to guarantee the quality of our products and services and thereby help to facilitate your researches.... read more
Superparamagnetic iron oxide microbeads have broad applications in biomedicine such as magnetic cell isolation and biomolecules purification magnetic resonance imaging of diseased tissues magnetic immunoassay targeted delivery of drugs and antigens hyperthermia aided chemo/radiotherapy and so on. BOC Sciences offers high-quality superparamagnetic iron oxide microbeads. Our products include various-sized magnetic beads with different coupling groups for the conjugation of biomolecules. We have established a high-level platform that involves many scientists and a full set of instruments to guarantee the quality of our products and services and thereby help to facilitate your researches.... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
Organic fluorine compounds have had a profound impact on the development of bioactive for the modern pharmaceuticals market. It is estimated that up to 20% of pharmaceuticals prescribed or administered in the clinic contain a fluorine atom and 30% of the leading 30 blockbuster drugs by sales contain a fluorine. BOC Sciences has major skills and a high degree of expertise in the field of fluorinated organic and inorganic chemicals providing a creative and innovative range of building blocks reagents and compressed and liquefied gases. Using fluorination technology that is our specialty BOC Sciences offers contract manufacturing of fluorinated compounds... read more
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Organic fluorine compounds have had a profound impact on the development of bioactive for the modern pharmaceuticals market. It is estimated that up to 20% of pharmaceuticals prescribed or administered in the clinic contain a fluorine atom and 30% of the leading 30 blockbuster drugs by sales contain a fluorine. BOC Sciences has major skills and a high degree of expertise in the field of fluorinated organic and inorganic chemicals providing a creative and innovative range of building blocks reagents and compressed and liquefied gases. Using fluorination technology that is our specialty BOC Sciences offers contract manufacturing of fluorinated compounds... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
The linker that connects the cytotoxic drug to the mAb is a key determinant of ADC activity. These linkers covalently couple the cytotoxic drug to the antibody producing an ADC that should be relatively stable in circulation. Stability of the linker is important because it prevents damage to nontarget tissue through spontaneous release of the cytotoxic drug while maximizing tumor drug exposure. Upon internalization however the linkers should facilitate efficient drug release. Intracellular conditions such as the low-pH environment in lysosomes or the reducing environment of the cytosol can destabilize acid-labile hydrazone linkers or disulfide-based linkers respectively resulting in drug... read more
Tel:
The linker that connects the cytotoxic drug to the mAb is a key determinant of ADC activity. These linkers covalently couple the cytotoxic drug to the antibody producing an ADC that should be relatively stable in circulation. Stability of the linker is important because it prevents damage to nontarget tissue through spontaneous release of the cytotoxic drug while maximizing tumor drug exposure. Upon internalization however the linkers should facilitate efficient drug release. Intracellular conditions such as the low-pH environment in lysosomes or the reducing environment of the cytosol can destabilize acid-labile hydrazone linkers or disulfide-based linkers respectively resulting in drug... read more
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IRP Trucks, IFTA, FMSCA, ICC, UCR Illinois IRP Age has set up a shop in Lacartes Marketplace13 Apr 2024
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