Health / Pharmaceuticals
1,144 RESULTS WITHIN anywhere FROM Atlanta, United States
45-1 Ramsey Road, Shirley
Tel: 16313721052
Electron microscopy (EM) has become an extremely popular method for the ultrastructural study of macromolecules cells and tissues. With our in-house EM platform at Creative Biostructure we are mainly focused on the use of cryo-EM technique to determine the structure of large macromolecules and their complexes with small ligands proteins and nucleic acids. Other types of samples are also acceptable and can be handled with scanning electron microscopy (SEM) or transmission electron microscopy (TEM).... read more
Tel: 16313721052
Electron microscopy (EM) has become an extremely popular method for the ultrastructural study of macromolecules cells and tissues. With our in-house EM platform at Creative Biostructure we are mainly focused on the use of cryo-EM technique to determine the structure of large macromolecules and their complexes with small ligands proteins and nucleic acids. Other types of samples are also acceptable and can be handled with scanning electron microscopy (SEM) or transmission electron microscopy (TEM).... read more
45-1 Ramsey Road, Shirley
Tel: 16313721052
Cell membrane functions as a boarder of cell by separating it from the outside environment and the membrane proteins are the gateways to the cell. Nutrients ions waste products even DNA and proteins are transported into and out of cells by membrane proteins. Membrane proteins involve in many cellular functions including: signaling transduction cell adhesion cell motility transportation and cell communication. Given their important roles in cell functions membrane proteins are often considered to be perfect drugs targets. In fact about two-thirds of approved drugs target membrane proteins nevertheless these account for only a very small part of the potential... read more
Tel: 16313721052
Cell membrane functions as a boarder of cell by separating it from the outside environment and the membrane proteins are the gateways to the cell. Nutrients ions waste products even DNA and proteins are transported into and out of cells by membrane proteins. Membrane proteins involve in many cellular functions including: signaling transduction cell adhesion cell motility transportation and cell communication. Given their important roles in cell functions membrane proteins are often considered to be perfect drugs targets. In fact about two-thirds of approved drugs target membrane proteins nevertheless these account for only a very small part of the potential... read more
45-1 Ramsey Road, Shirley
Tel: 16313721052
Creative Biostructure offers high-throughput UniCrys™ crystallization services with our state-of-the-art facilities and has developed an X-ray crystallography pipeline including all the stages from gene synthesis to structure determination. Our experienced scientists can teamwork with customers and accelerate the research progress.... read more
Tel: 16313721052
Creative Biostructure offers high-throughput UniCrys™ crystallization services with our state-of-the-art facilities and has developed an X-ray crystallography pipeline including all the stages from gene synthesis to structure determination. Our experienced scientists can teamwork with customers and accelerate the research progress.... read more
45-1 Ramsey Road, Shirley
Tel: 16313721052
Creative Biostructure now can provide a collection of tools and analysis package for biomolecular structure determination refinement and analysis from crystallographic EM or NMR data. In structural biology field in order to reveal a dedicated and reliable structure of biomolecule research data is acquired interpreted published reused and sometimes eventually discarded. Creative Biostructure helps the development of appropriate infrastructural services ones which make it easier and time-saving for researchers to collect read and process the data and obtain the expected and target structure results.... read more
Tel: 16313721052
Creative Biostructure now can provide a collection of tools and analysis package for biomolecular structure determination refinement and analysis from crystallographic EM or NMR data. In structural biology field in order to reveal a dedicated and reliable structure of biomolecule research data is acquired interpreted published reused and sometimes eventually discarded. Creative Biostructure helps the development of appropriate infrastructural services ones which make it easier and time-saving for researchers to collect read and process the data and obtain the expected and target structure results.... read more
45-1 Ramsey Road, Shirley
Tel: 16313721052
Proteins are the building blocks of all living organisms and play crucial roles in biological processes. To investigate how a particular protein modulates biological processes many aspects of the protein such as structure modification localization interaction and function needs to be studied. A considerable number of proteins especially membrane proteins are screened in drug discovery as biological targets or as potential drugs themselves. Most of these proteins are produced using cell-based or cell-free expression systems which typically includes the transcription of recombinant DNA into mRNA that is further translated into the protein under study. Creative Biostructure uses both cell-based and... read more
Tel: 16313721052
Proteins are the building blocks of all living organisms and play crucial roles in biological processes. To investigate how a particular protein modulates biological processes many aspects of the protein such as structure modification localization interaction and function needs to be studied. A considerable number of proteins especially membrane proteins are screened in drug discovery as biological targets or as potential drugs themselves. Most of these proteins are produced using cell-based or cell-free expression systems which typically includes the transcription of recombinant DNA into mRNA that is further translated into the protein under study. Creative Biostructure uses both cell-based and... read more
45-16 Ramsey Road, Shirley, NY
6-Aminoquinoline-N-hydroxy-succinimidyl carbamate is suitable for amino acid or protein sequence analysis by HPLC with fluorescence detection. You can find this chemical at BOC Sciences. (www.bocsci.com)... read more
6-Aminoquinoline-N-hydroxy-succinimidyl carbamate is suitable for amino acid or protein sequence analysis by HPLC with fluorescence detection. You can find this chemical at BOC Sciences. (www.bocsci.com)... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
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Triheptanoin is a triglyceride that is used for the treatment of inherited metabolic diseases epilepsy ventricular hypertrophy and myocardial glucose oxidation. You can find this chemical at BOC Sciences. (www.bocsci.com)... read more
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Triheptanoin is a triglyceride that is used for the treatment of inherited metabolic diseases epilepsy ventricular hypertrophy and myocardial glucose oxidation. You can find this chemical at BOC Sciences. (www.bocsci.com)... read more
45-16 Ramsey Road, Shirley, NY
Favipiravir also known as T-705 or Avigan is an experimental antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses. Like some other experimental antiviral drugs (T-1105 and T-1106) it is a pyrazinecarboxamide derivative. Favipiravir is active against influenza viruses West Nile virus yellow fever virus foot-and-mouth disease virus as well as other flaviviruses arenaviruses bunyaviruses and alphaviruses. Activity against enteroviruses and Rift Valley fever virus has also been demonstrated.... read more
Favipiravir also known as T-705 or Avigan is an experimental antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses. Like some other experimental antiviral drugs (T-1105 and T-1106) it is a pyrazinecarboxamide derivative. Favipiravir is active against influenza viruses West Nile virus yellow fever virus foot-and-mouth disease virus as well as other flaviviruses arenaviruses bunyaviruses and alphaviruses. Activity against enteroviruses and Rift Valley fever virus has also been demonstrated.... read more
45-16 Ramsey Road, Shirley, NY
Purmorphamine under the IUPAC name 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine is a cell-permeable 6 9-trisubstituted purine which directly binds and activates Smoothened (in HEK293T cell:IC50= ~ 1.5 μM ).So it has been shown to activate the Hedgehog (Hh) signaling pathway which is important for regulating embryonic patterning stem cell renewal and tissue regeneration. In vitro: An activator of the hedgehog (Hh) signaling pathway by directly binds and activates Smoothened (in HEK293T cell:IC50= ~ 1.5 μM ). In vivo: Purmorphamine up-regulates ALP expression in human mesenchymal stem cell-based constructs on rats.... read more
Purmorphamine under the IUPAC name 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine is a cell-permeable 6 9-trisubstituted purine which directly binds and activates Smoothened (in HEK293T cell:IC50= ~ 1.5 μM ).So it has been shown to activate the Hedgehog (Hh) signaling pathway which is important for regulating embryonic patterning stem cell renewal and tissue regeneration. In vitro: An activator of the hedgehog (Hh) signaling pathway by directly binds and activates Smoothened (in HEK293T cell:IC50= ~ 1.5 μM ). In vivo: Purmorphamine up-regulates ALP expression in human mesenchymal stem cell-based constructs on rats.... read more
45-16 Ramsey Road, Shirley, NY
Cyt387 also called Momelotinib under the IUPAC name N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide is an ATP competitive inhibitor of JAK1 (IC50 = 11 nM) and JAK2 (IC50 = 18 nM) with potential antineoplastic activity which may result in the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells. You can find this chemical at BOC Sciences. (www.bocsci.com)... read more
Cyt387 also called Momelotinib under the IUPAC name N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide is an ATP competitive inhibitor of JAK1 (IC50 = 11 nM) and JAK2 (IC50 = 18 nM) with potential antineoplastic activity which may result in the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells. You can find this chemical at BOC Sciences. (www.bocsci.com)... read more
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