Health / Pharmaceuticals
1,144 RESULTS WITHIN anywhere FROM Warmley, United Kingdom
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 0631 619 7922
Salcaprozate sodium (SNAC) (sodium 8-((2-hydroxybenzoyl)amino) octanoate CAS RN 203787-91-1) is classified as an oral absorption promoter. Although several clinical investigations have explored the potential therapeutic applications of SNAC as a delivery agent for oral forms of heparin and insulin limited information about the nonclinical safety of SNAC itself was found in the published scientific literature. In a published review article on the development of an oral heparin formulation the results of SNAC toxicological studies are given but the item provides no details regarding their conduct.... read more
Tel: 0631 619 7922
Salcaprozate sodium (SNAC) (sodium 8-((2-hydroxybenzoyl)amino) octanoate CAS RN 203787-91-1) is classified as an oral absorption promoter. Although several clinical investigations have explored the potential therapeutic applications of SNAC as a delivery agent for oral forms of heparin and insulin limited information about the nonclinical safety of SNAC itself was found in the published scientific literature. In a published review article on the development of an oral heparin formulation the results of SNAC toxicological studies are given but the item provides no details regarding their conduct.... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 0631 619 7922
Temocillin is a β-lactam antibiotic active against gram-negative bacteria including β-lactamase producers. It is currently indicated for the treatment of septicemia urinary tract infections and lower respiratory tract infections. In the recent years the interest on this drug has been greatly enhanced due to the increased incidence of infections caused by microorganisms producing extended-spectrum β-lactamases. This makes temocillin a strategic and interesting alternativeto carbapenems especially with the current driving force to spare the use of these drugs. Pharmacodynamic studies predict that therapeutic success with β-lactams depends on the time during which their unbound concentration in serum remains above the MIC... read more
Tel: 0631 619 7922
Temocillin is a β-lactam antibiotic active against gram-negative bacteria including β-lactamase producers. It is currently indicated for the treatment of septicemia urinary tract infections and lower respiratory tract infections. In the recent years the interest on this drug has been greatly enhanced due to the increased incidence of infections caused by microorganisms producing extended-spectrum β-lactamases. This makes temocillin a strategic and interesting alternativeto carbapenems especially with the current driving force to spare the use of these drugs. Pharmacodynamic studies predict that therapeutic success with β-lactams depends on the time during which their unbound concentration in serum remains above the MIC... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 0631 619 7922
Synonyms 5' 5'-Dinitro-3' 3'-diiodo-3 4 5 6-trtrabromophenol-sulfonephthalein; DIDNTB Find DIDNTB at BOC Sciences. BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors building blocks GMP Products impurities and metabolites APIs for Veterinary Natural Compounds ADCs Stem Cell Molecule and chiral compounds. Over eight years of successful operation in the pharmaceutical industry has enabled us to possess a full-bodied array of building blocks in numerous pack sizes. BOC Sciences is constantly seeking to expand our product lines by incorporating additional potential drug like molecules.... read more
Tel: 0631 619 7922
Synonyms 5' 5'-Dinitro-3' 3'-diiodo-3 4 5 6-trtrabromophenol-sulfonephthalein; DIDNTB Find DIDNTB at BOC Sciences. BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors building blocks GMP Products impurities and metabolites APIs for Veterinary Natural Compounds ADCs Stem Cell Molecule and chiral compounds. Over eight years of successful operation in the pharmaceutical industry has enabled us to possess a full-bodied array of building blocks in numerous pack sizes. BOC Sciences is constantly seeking to expand our product lines by incorporating additional potential drug like molecules.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
This assay system utilizes HEK293t cells that express NF-κB (nuclear factor kappa-lightchain enhancer of activated B cells) and contain the luciferase reporter gene functionally linked to upstream NF-κB genetic response elements. Thus quantifying changes in luciferase expression provides a sensitive surrogate measure of changes in the level of NF-κB activation. NF-κB is a signal transduction dependent transcription factor. This NF-κB reporter cell line is validated to provide a robust dose-dependent activation response when treated with TNFɑ or the Protein Kinase C activator Phorbol 12-myristate 13-acetate (PMA). As such the principle application of this assay system is in the screening of... read more
This assay system utilizes HEK293t cells that express NF-κB (nuclear factor kappa-lightchain enhancer of activated B cells) and contain the luciferase reporter gene functionally linked to upstream NF-κB genetic response elements. Thus quantifying changes in luciferase expression provides a sensitive surrogate measure of changes in the level of NF-κB activation. NF-κB is a signal transduction dependent transcription factor. This NF-κB reporter cell line is validated to provide a robust dose-dependent activation response when treated with TNFɑ or the Protein Kinase C activator Phorbol 12-myristate 13-acetate (PMA). As such the principle application of this assay system is in the screening of... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
This gene encodes a polypeptide hormone precursor that undergoes extensive tissue-specific post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and depending on tissue type and the available convertases processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin essential for normal steroidogenesis and the maintenance of normal adrenal weight and lipotropin beta are the major end products. In other tissues including the... read more
This gene encodes a polypeptide hormone precursor that undergoes extensive tissue-specific post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and depending on tissue type and the available convertases processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin essential for normal steroidogenesis and the maintenance of normal adrenal weight and lipotropin beta are the major end products. In other tissues including the... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein the VAV1 oncoprotein and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq Feb 2011]... read more
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein the VAV1 oncoprotein and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq Feb 2011]... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region composed of three immunoglobulin-like domains a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors setting in motion a cascade of downstream signals ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast... read more
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region composed of three immunoglobulin-like domains a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors setting in motion a cascade of downstream signals ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Official Full Nametransforming acidic coiled-coil containing protein 3 BackgroundThis gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. SynonymsTACC3; transforming acidic coiled-coil containing protein 3; transforming acidic coiled-coil-containing protein 3; ERIC1; ERIC-1; MGC117382; MGC133242... read more
Official Full Nametransforming acidic coiled-coil containing protein 3 BackgroundThis gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. SynonymsTACC3; transforming acidic coiled-coil containing protein 3; transforming acidic coiled-coil-containing protein 3; ERIC1; ERIC-1; MGC117382; MGC133242... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
RNA Isolation is frequently used in molecular biological experiments. The most important thing for isolate RNA is that you must protect RNA from degradation by RNAase. Here is a brief protocol to isolate RNA from leaf tissue.... read more
RNA Isolation is frequently used in molecular biological experiments. The most important thing for isolate RNA is that you must protect RNA from degradation by RNAase. Here is a brief protocol to isolate RNA from leaf tissue.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Members of the transforming growth factor β (TGF-β) superfamily are highly conserved across animals. They are found in both vertebrates and invertebrates are ubiquitously expressed in diverse tissues and function during the earliest stages of development and throughout life. The TGF-β superfamily of secreted factors comprises more than 30 members including activins nodals bone morphogenetic proteins (BMPs) and growth and differentiation factors (GDFs). Members of the TGF-β superfamily exert their effects by binding to specific serine/threonine kinase type I and type II receptor complexes. These receptors known as TGF-β type I and type II receptors or TβR-I and TR-II are... read more
Members of the transforming growth factor β (TGF-β) superfamily are highly conserved across animals. They are found in both vertebrates and invertebrates are ubiquitously expressed in diverse tissues and function during the earliest stages of development and throughout life. The TGF-β superfamily of secreted factors comprises more than 30 members including activins nodals bone morphogenetic proteins (BMPs) and growth and differentiation factors (GDFs). Members of the TGF-β superfamily exert their effects by binding to specific serine/threonine kinase type I and type II receptor complexes. These receptors known as TGF-β type I and type II receptors or TβR-I and TR-II are... read more
BUSINESS CATEGORIES
Acupuncture
· Addiction Treatment & Rehab Clinics
· Cardiologists
· Chiropractors
· Clinics
· Counselling Services
· Dental Products
· Dentists
· Dermatologists
· Disability Equipment & Services
· Fertility Services
· Health Products
· Health Tourism
· Holistic, Alternative & Naturopathic Medicine
· Hospitals
· Hypnotherapy
· Medical Devices
· Mental Health
· Mobility Aids
· Nutrition & Dietitians
· Obstetricians & Gynaecologists
· Ophthalmologists
· Optometrists
· Orthodontists
· Osteopathy
· Paediatricians
· Pathologist
· Pharmaceuticals
· Pharmacy
· Physiotherapy
· Podiatry
· Pregnancy & Maternity Services
· Speech Therapy
· Sports Medicine
POPULAR LOCATIONS
London
· West Midlands
· Surrey
· Kent
· Manchester
· Essex
· Lancashire
· Hampshire
· West Yorkshire
· Hertfordshire
· Berkshire
· Cheshire
· West Sussex
· Buckinghamshire
· East Sussex
· Bristol
· Devon
· Nottinghamshire
· Merseyside
· North Yorkshire
· Dorset
· Oxfordshire
· Leicestershire
· Glasgow
· Derbyshire
· South Yorkshire
· Edinburgh
· Cambridgeshire
· Staffordshire
· Somerset
· Tyne and Wear
· Norfolk
· Wiltshire
· Gloucestershire
· Warwickshire
· Bedfordshire
· Lincolnshire
· Northamptonshire
· Suffolk
· Cardiff
· Cornwall
· Worcestershire
· Durham
· Cumbria
· Herefordshire
· Belfast
· Shropshire
· Highland
· Aberdeenshire
· East Riding of Yorkshire
News Feeds
-
-
IRP Trucks, IFTA, FMSCA, ICC, UCR Illinois IRP Age has set up a shop in Lacartes Marketplace13 Apr 2024
-
-
-